Civil war broke out in 1455, leading to a long period of dynastic conflict known as the Wars of the Roses. Henry was deposed on 29 March 1461 after a crushing defeat at the Battle of Towton by Richard's son, who took the throne as Edward IV. Despite Margaret continuing to lead a resistance to Edward, Henry was captured by Edward's forces in 1465 and imprisoned in the Tower of London. Henry was restored to the throne in 1470, but Edward retook power in 1471, killing Henry's only son and heir, Edward of Westminster, in battle and imprisoning Henry once again.  Having "lost his wits, his two kingdoms, and his only son", Henry died in the Tower during the night of 21 May, possibly killed on the orders of King Edward. (Wikipedia)